Abstract Alumina is a polymorphic bioceramic that has been extensively investigated for application in bone regeneration. Dense α-alumina has been considered a suitable biomaterial for dental and orthopedic implants due to its superior mechanical properties. However, its use is limited due to its high inertia in a biological environment. Recent investigations have focused on its distinct phases and surface characteristics through the control of morphology, physical properties, and chemical composition to enhance bioactivity. This article presents a brief review of the developments in porous α-alumina and amorphous-γ-alumina transition. Most studies have shown that composites and alumina coated with bioactive materials, high surface area, and hydroxylated surface can significantly improve biological properties. Cellular responses such as fixation, growth, and proliferation, as well as biomineralization, are the main studies to validate improvements in bioactive properties.

Resumo Esse trabalho mostra a produção de nanofibras de alumina após tratamento térmico de fibras híbridas preparadas por fiação por sopro em solução. Essas nanofibras foram convertidas em γ-Al2O3 e α-Al2O3 após tratamento térmico ao ar entre 500 e 1200 °C. Os padrões de difração de raios X apresentaram todas as características das fases alumina γ e α. Além disso, as micrografias eletrônicas de varredura mostraram que os diâmetros das nanofibras de alumina variaram entre 200 e 270 nm para diferentes temperaturas. Os resultados demonstraram que o método de fiação por sopro em solução é eficiente para produzir nanofibras de alumina.

Abstract This work shows the successful production of alumina nanofibers after thermal treatment of solution blow spun hybrid fibers. These nanofibers were converted into γ-Al2O3 and α-Al2O3 after the thermal treatment in air between 500 to 1200 °C. The X-ray diffraction patterns presented all the characteristics of the γ and α phases of alumina. In addition, the scanning electron micrographs showed alumina nanofiber diameters varying between 200 and 270 nm for different temperatures. The results demonstrated that the solution blowing spinning method is efficient to produce alumina nanofibers.